The state could just arrest the federal agents for breaking state law, and throw them in with the drug dealers and stall the fed's efforts to spring them with maximal paperwork.
Let the 'system' sort them out and see how keen they are.
Only in regards to things where the federal government has authority to begin with. There are very good reasons (the Enumerated Powers clause, the 9th and 10 amendments, etc.) to question if the federal government actually has all the authority it claims for itself.
That’s true, but it’s been squarely presented and decided in Reich v Gonzales, relying on Wickard v Filburn that Congress does have this power. And through application of stare decisis / precedent it will be difficult to undo that.
Let the 'system' sort them out and see how keen they are.