Do you have evidence that ayuhuasca is mutagenic? Inhibition of enzymes is temporary and generally harmless if you are careful not to consume certain drugs while inhibited.
Not I, though Dr. Shulgin says;
"The second question relates to yet another beta-carboline alkaloid, Harman. This is a structural analogue of Harmine that has been stripped of its methoxyl group. It is widely found in plants and foods, and has been shown in experimental animals to be a vasodilator and a hypotensive agent. It also interacts directly with DNA and is thus a possible mutagenic agent."
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