Some prerequisites to using this information: * You must be sending HTML, not text, emails.
http://news.ycombinator.com/item?id=1500488
It's not spammy but it does include graphics, colors, layouts, etc. Also I could be wrong but I think using an html email gives you a more accurate open rate.
Sure some people can misuse html email's but I don't think they are all bad.
http://news.ycombinator.com/item?id=1500488