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This is really exciting news.

However, a big challenge that makes this work extremely difficult to bring to fruition is that you have to let an embryo develop fully to figure out to determine if the therapy actually produces a healthy human. At which point the consequences of failed experiments become increasingly difficult to work with for obvious ethical and moral reasons.




They did let them grow for 5 days which should have provided some data. Though what I don't get is why were they destroyed after 5 days? If it's considered ethical to allow abortions for periods up to 20+ weeks, then it should be considered ethical for science as well.


The practical reason is it's not clear how long they would survive. These embryos are in a petri dish, unless they were to implant them in a women's uterus I'm not sure how long they would be able to develop.

You might be able to develop them longer than five days, but then you hit the ethical issues. The entire moral argument for abortions is based on bodily autonomy of women, and that those rights trump the rights of an unborn fetus. But for raising a fetus in an artificial environment there is no body autonomy argument.

Another issue is murkier, and is based on the circumstances. Generally abortions are used by women who did not intend to get pregnant as a last resort form of birth control. When you're performing abortions for scientific purposes it's different, and there are different ethical standards to consider.


I think i would put the same importance on the well-being of a women and scientific progress.

One shouldn't trump the other.


The issue would be abortions for periods up to 20+ weeks considered ethical by whom?

There's nowhere near consensus on that issue in society. Also the ethics of abortion wouldn't be the same as the ethics of such experiments; in abortion the rights of the mother are at play, minimally, and there are reasonable discussions about when an embryo obtains rights as well as whose rights reign supreme.

Even if considered legal, given that law != ethics, the balance of rights is not the same as abortion.

I would also expect the scientists to deal with this pretty conservatively because if they push those limits, the likely cries to stop funding, etc, etc, would become much more pronounced and the likelihood of the work hitting a political wall much higher.


Currently there's limits on how long you can keep embryos going -- the '14-day rule':

http://www.nature.com/news/embryology-policy-revisit-the-14-...

Will be interesting to see the moral and ethical debate on any change here.


There is a Radiolab episode about this too. They talk about all of the things that we don't know about that happen between days 14 and ~30 (working from memory), and also how the person who came up with the 14 day rule chose that number at least in part because, at the time, it was way out of reach and did not seem like it would ever be achievable.

http://www.radiolab.org/story/primitive-streak/


Uh no? Pregnancy is usually not an elective experiment. Standards are much higher for experiments, c.f. standards applied to human subject studies vs. medical treatment.




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