I should know, I'm using a QWERTZ keyboard. But those are not all keyboard layouts: QÜERTY, ÄWERTY, QZERTY, DVORAK, BÉPO, JCUKEN, WORKMAN, ŪGJRMV, MALTRON, etc.
Then there are the asian and middle east that do not even use the same alphabet. Though those may use the QWERTY as an underlying layout for compatibility.