If your site has a lot of image content, I'd love for you to try out PLEENQ (http://pleenq.com). It doesn't inconvenience your users, and in fact helps them buy things directly from your images. You can also use it on top of any of the advertising you're currently using (or even donations if you move to that).
They need to mapped individually, but it's a really simple interface to do it. I've also just added a templating system that allows you to customize all aspects of the popup, and am about to go live with a split test system that lets you split test multiple items to the same region.
Here's a site using it for their lifestyle blog -- hover over the first image (desktop only): https://www.theskinnyconfidential.com/2016/11/04/bridal-show...
Email me at justin@pleenq.com if you have any questions!