Are you talking about https://tweetdeck.twitter.com/ or a desktop or mobile app? I think tweetdeck.twitter.com is my preferred Twitter UI because it allows me to keep on top of keyword searches as well.
Staying on top of current conversations and trends in a niche area of web design is a big chunk of Twitter's value to me and it's very time consuming to do that in their mobile app or regular Twitter.com
They have taken a great tool and striped it so that it fits their blurry vision of what the service should look like.