I wouldn't, but I know a number of people who do. Or, people who have a toilet, but don't use it because they park off-the-grid for long periods of time. It's do-able.

When I've wanted to live in cities without a nearby RV park, I have been known to use a gym for shower/toilet (when I was moving around a lot more often than I do now, I had an all-club membership at 24 Hour Fitness; Planet Fitness is a better deal now, but they have a lot fewer clubs), so I could extend my time between driving to a dump station.