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"Further, no difference was found in HFCS intake and total overall caloric intake in the groups given 12-h access versus 24-h access. Both groups consumed the same amount of HFCS on average (21.3 ± 2.0 kcal HFCS in 12-h versus 20.1 ± 1.6 kcal HFCS in 24 h), even though only the 12-h group showed a significant difference in body weight when compared with the control groups."

As per the author's criticism, these results are seemingly inconsistent. Why would rats with 12-h access to HFCS gain more weight while rats with 24-h access did not, when their HFCS intake was the same on average?




The say on page 2: "...our previous publications show limited (12 h) access to sucrose precipitates binge-eating behavior (Avena et al., 2006)."


Perhaps the liver or some part of the digestive system can only handle a certain amount of HFCS per hour.


When I eat too much cake, I like to stop too ;-)

I realize that's not scientific. I'm just saying the inconsistency is not a smoking gun, and was addressed within the paper.




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