I guess the most obvious thing is what it not has, which is a massive GUI. It is much faster to work with when you know what you are looking for in my opinion. In most cases running wireshark without tcpdump first is really inadequate.
My usage or Wireshark is rather sporadic, so I appreciate the traffic drill down I can do w/o any knowledge in advance about the protocols I have captured.
Article about wireshark :)