I don't see why they didn't just have them consume food with oil in it, this seems like a highly unnatural delivery mechanism.
Relevant comment from Ars:
> Interesting to note... If you look at the study
> "THC (THC Pharm) was diluted in 0.9% NaCl
(saline) solution containing 3% (vol/vol) DMSO and 2% (vol/vol)
Tween-80 and administered intraperitoneally (i.p.) at a final dose of 3 mg/kg to pregnant females for 5 consecutive days, from E12.5 to E16.5. Control mice were injected with vehicle solution."
> DMSO is TOXIC to developing brains. Its actually recommended not to use it in studies because it causes too much damage.
> "The in vitro results suggest avoiding the use of BeOH (which also is more toxic than the other solvents in the in vivo test) and DMSO and using PEG400, EtOH and DMF even though the latter induced a body weight decrease in the B6D2F1 mouse strain. "
Relevant comment from Ars:
> Interesting to note... If you look at the study
> "THC (THC Pharm) was diluted in 0.9% NaCl (saline) solution containing 3% (vol/vol) DMSO and 2% (vol/vol) Tween-80 and administered intraperitoneally (i.p.) at a final dose of 3 mg/kg to pregnant females for 5 consecutive days, from E12.5 to E16.5. Control mice were injected with vehicle solution."
> DMSO is TOXIC to developing brains. Its actually recommended not to use it in studies because it causes too much damage.
> "The in vitro results suggest avoiding the use of BeOH (which also is more toxic than the other solvents in the in vivo test) and DMSO and using PEG400, EtOH and DMF even though the latter induced a body weight decrease in the B6D2F1 mouse strain. "
> http://www.ncbi.nlm.nih.gov/pubmed/8011014
> It would seem as though they purposefully paired the THC with a solvent that would cause the relevant brain abnormalities.