I used Autodesk Inventor w/ HSMWorks for the physical enclosure (both packages have 30 day free trials).

For the PCB, I tried using Eagle (very tedious / confusing) and KiCAD (couldn't figure out how to install on OS X without compiling from source) and ended up using Altium Designer via a friend's dad, who is an electrical engineer. Unlike Inventor / SolidWorks, Altium was very tedious and confusing and I was stuck until I bought an excellent video course on the topic: http://www.fedevel.com/academy/