My father doesn't eat sweets. He has a very healthy diet - whole grains, vegetables, etc. Never had a cavity nor gum disease.
Because of that he never went to the dentist to have a check up.
He ended up loosing all his teeth from hardened plaque below the gum line.
His teeth just fell off, one after another, because he never learned good dental hygiene.
At least in the US, the argument is that when pressed by the FDA, Novamin was pulled from the market by GlaxoSmithKline instead of doing the required trials whereas Biomin went through and passed all the trials.
And since it's actually gone through the process, there are studies out that compare it to other hydroxyapatite solutions. I've linked one study which compares their two variants against Apacare and karex (two HAp toothepaste which have studies of their own that compare against the others before them like Novamin).
The study shows that Biomin C (the one without Fluoride) is comparable to karex (the one without fluoride) and other similar HAp toothepastes. HAp + fluoride (like novamin) marginally outperforms it. So if you use fluoride (such as by also using a fluoride toothpaste or living in an area with fluoride in the water) the difference should be negligible. Importantly though for people in the US, Biomin C is available here.
Biomin F is wrapping up the FDA approval process however it does seem to generally outperform all other formulations since the fluoride is actually part of the bioglass itself rather than simply an additional active ingredient in the suspension.
TLDR: Biomin C is within marginal differences to comparable no-fluoride HAp toothpastes on the market but Biomin F outperforms other HAp toothpastes that contain fluoride since the fluoride in Biomin F is delivered via the same mechanism that handles remineralisation of the other elements. And to my knowledge Biomin F is the only HAp toothpaste to do that so far. Also Biomin C is the only HAp toothpaste available in the US (with Biomin F apparently soon to follow).
I had severe GERD for years. On an off PPI's for almost 5 years, several endoscopies, pain 24h per day.
It was so the bad I almost went for surgery.
Then I tried the low fodmap diet and it went away.
Now I only have to avoid alcohol, onions, garlic and sweet fruits to keep it at bay.
A few friends who started reporting GERD all the time at the start of the pandemic, didn't make the connection between working and eating in bed or the sofa at times, and the gradual worsening, compounded with the usual inflammatory foods and sleeping on the wrong side or without any inclination, the body's buffer depletes so to speak and those issues appear more frequently.
They can't debug the airframe change (moved the new big fans forward). That should have triggered a new type certification. Instead we got a software coverup which the regulators OK'd so the airlines would not have to pay for pilot training on a new aircraft type.
I have been working on a game as a side project for 10 years now. Why such a long time? It started when I was freelancing and carried on through full-time jobs, a marriage and now a small child. I am lucky if I can get one hour a day to work on it - but as others mentioned here, the best time to work on it is before your main job, otherwise I am too tired to code after a full day of software development, childcare, and home chores.
I really wish I can finish it some day and show it here.
As someone who as been taking these for 3+ years and is utterly scared of these news I would just like to add a few data points regarding my experience that might help others:
- an endoscopy revealed level 1 oseophagitis
- triggers for me include: coffee, tea or any other source of caffeine, fried and high fat foods, alcohol, acidic fruits, high protein foods.
- an experiment with betaine HCL + pepsin was very painful. After that I learned that pepsin is as bad or worse to your oesophagus than stomach acid.
- cider vinegar: same result as betaine HCL + pepsin.
- digestive enzymes: no change.
- pro-biotics, including kefir: no change.
- cutting gluten, dairy and sugar: no change.
- ranitidine: works but effectiveness drops rapidly.
- on-going experiments: liquorice and low-fodmap diet, no conclusions yet.
went through almost all of your points actually. though my symptoms were "gastro-attacks" of frightening intensity where i'd end up in hospital. ended up having gallbladder removed after test showed it very-low functioning and had complete recovery. took PPI's still intermittently, but tapered off after a couple years.
That's only ~187MP/s. A single 4k 2160p60 stream needs almost 500MP/s, which might be at the edge of what's possible on a CPU today, but would make far more sense for a GPU to do.
It shouldn't be a stretch for a quad-core desktop processor today. Doubling the core count and increasing clock speed by 40% compared to a mobile Core 2 isn't hard. DDR4 instead of DDR2 means memory bandwidth is probably not an issue, and AVX can probably provide further headroom on the compute power.
And, of course, it's much easier to build a desktop with far more than four CPU cores these days.
This is very cool!
In 1999 my degree final year project was to implement an mpeg decoder in software.
My only source of information was the MPEG technical reference manuals.
It took me 3 months to be able to decode my first frame.
It ran at less than 10fps on an AMD K6, but I learn a lot about video and compression.
I did exactly the same, but instead purely for fun and learning. Picked a random/blind clip from a naughty movie for extra motivation to get the first frames to the screen :D
I also worked from just the reference book, with no prior knowledge of video coding at all, which made it quite a puzzle to get something on the screen and moving, but it was extremely satisfying when it all worked (to some extent, the thing was horribly slow, broke after one group of predicted frames, and I never implemented chroma, just luma)
