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"Colorectal cancer (bowel cancer) is the third most common form of cancer worldwide, with around 1.9 million newly diagnosed cases and 900,000 deaths every year. Therefore, preventive substances represent an urgent clinical need. Aspirin/acetylsalicylic acid has proven to be one of the most promising candidates for the prevention of colorectal cancer. Among other findings, studies have shown that when patients with cardiovascular diseases took low doses of aspirin over several years, it reduced their risk of colorectal cancer. Furthermore, aspirin can inhibit the progression of colorectal cancer. Now a team led by Heiko Hermeking, Professor of Experimental and Molecular Pathology at LMU, has investigated which molecular mechanisms mediate these effects."


"Meta CEO Mark Zuckerberg allegedly halted proposals aimed at improving Facebook and Instagram’s impact on teen mental health, according to internal communications revealed as part of unsealed court documents.

Zuckerberg allegedly vetoed plans to ban filters that simulate plastic surgery on Meta-owned platforms, according to the unredacted lawsuit filed by Massachusetts Attorney General Andrea Campbell (D), and ignored requests from top executives to boost investments in teens’ well-being."


"In the fall of 2021 a consultant named Arturo Bejar sent Meta Chief Executive Mark Zuckerberg an unusual note.

“I wanted to bring to your attention what l believe is a critical gap in how we as a company approach harm, and how the people we serve experience it,” he began. Though Meta regularly issued public reports suggesting that it was largely on top of safety issues on its platforms, he wrote, the company was deluding itself.

The experience of young users on Meta’s Instagram—where Bejar had spent the previous two years working as a consultant—was especially acute. In a subsequent email to Instagram head Adam Mosseri, one statistic stood out: One in eight users under the age of 16 said they experienced unwanted sexual advances on the platform over the previous seven days."


> One in eight users under the age of 16 said they experienced unwanted sexual advances on the platform over the previous seven days.

I wonder what % of these is "show bobs and vegana" which is more of a nuisance than a threat.


What world are you living in where asking children under 16 to share pictures of their private sexual body parts is a “nuisance”? Epstein, is that you?


Most businesses need to buy their raw materials to produce their products. With Meta, the raw material is consumer data, which users have been giving away to Meta freely.

The fines only slightly raise the cost of this raw material from $0, so it's unlikely to deter Meta's behavior until someone faces a more severe penalty there.


Strip mining users since 2004!


"We are excited to announce the release of XGBoost 2.0. This note will begin by covering some overall changes and then highlight specific updates to the package..."


For those of you interested in reading about work being done to start a new city (1) or new semi-autonomous country (2) where people can plan something new, St Helena Island sounds like a good candidate- remote but can still in the middle of several trade routes.

(1) https://apnews.com/article/silicon-valley-tech-investors-new...

(2) https://www.wired.com/story/itana-binance-charter-cities-ins...


Perhaps there is technology for building these devices or data collected by them that someone wants.

This might be a theft disguised as a mere takedown.


.High-energy laser weapons can now operate ‘infinitely’, thanks to a new cooling system that completely eliminates the build-up of waste heat

.The technology could significantly change the face of battle by extending engagement times, and increasing range and damage, researchers say


The C language is like 'an elegant weapon for a more civilized age.'

This article reminds me of an idea I once had: to write a memory manager/garbage collector for C. The challenge is to know the scope of a dynamically managed chunk of memory. Using that, the memory can be automatically garbage-collected, but this is difficult since C wasn't designed for this in mind.

I'm curious if anyone has any other experiences they can share.



I did this once - a compacting collector for C. it was a really trivial mark/sweep - and as I recall you had to write functions for each type to perform the object graph traversal. for artificial memory-intensive workloads it was around 8x the performance of boehm.


Is this anything you'd be willing to share publicly?

How did you determine the scope of a chunk of memory? I believe you need this to run any of the GC algorithms.

I checked the hboehm documentation (1) and in the section on "Locating roots" it says "you don't want to know":

-Runtime stack(s): you don't really want to know.Need consistent caller-save reg. snapshot

-Static data segments: you don't want to know that either.

-Very platform dependent • But you only have to do it once per platform.

(1) https://www.hboehm.info/gc/04tutorial.pdf


yeah, of course. its old crap that I'd have to find if I can. I will look.

roots in boehm means globals and the stack. this little thing had explicitly declared roots.

edit: I found it, mail me at yuri@tenuki.org. be prepared to be unimpressed.


That was my first reaction as well, I haven't really used it, but it's an interesting tool.



-Nvidia announced a new chip designed to run artificial intelligence models on Tuesday .

-Nvidia’s GH200 has the same GPU as the H100, Nvidia’s current highest-end AI chip, but pairs it with 141 gigabytes of cutting-edge memory, as well as a 72-core ARM central processor.

-"This processor is designed for the scale-out of the world’s data centers," Nvidia CEO Jensen Huang said Tuesday.


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