My daughter died of AML earlier this year. AML is unfortunately much harder to treat than ALL. She was treated for almost three years (it came back twice). We "lived" with her in the hospital for around 1,5 years over that three year period.
Many of the chemo medications she got have been a stable of AML treatment for decades. From what I understood from our doctors, the improvement in survival rate for AML has come from supportive care, i.e. the ability to keep the patient alive during treatment. Treatment of bacterial and fungal infections has gotten a lot better.
AML is a very heterogeneous disease. The treatment depends a lot on the specific mutations the patient has. Research can only focus on so many target mutations at a time. We did see the progress over the three years we were there. I have high hopes that children with the same mutation as my daughter will in the near future have better chances, specifically thanks to menin inhibitors.
Highstreet Mobile Retail | Utrecht (near Amsterdam), The Netherlands | Onsite/Remote (EU) | Full Time
We're looking for Backend, iOS & Android Engineers. Our mission with Highstreet is to connect people to the brands they love. We are a team of makers and we've built a native app SaaS product for fashion brands. We enable brands to give an amazing shopping experience to their customers. Our customers get a native mobile shopping app for Android and iOS and that app constantly gets better.
- Backend Engineer: design and develop the Highstreet API, the beating heart of our product. Stack: Ruby / Sinatra / Minitest / Redis / OpenAPI / PostgreSQL / Go / Kubernetes / GCP / Gitlab CI. Contact the back-end lead directly at vincent@highstreetmobile.com.
- iOS/Android Engineer: work on the native core library that powers our 25+ native apps. We use RxSwift/RxJava, SwiftUI, Kotlin, Dagger. Contact the mobile lead directly at thomas@highstreetmobile.com.
Highstreet Mobile | Android Engineer | Utrecht (near Amsterdam), The Netherlands | Onsite/Remote (EU) | Full Time | https://www.highstreetmobile.com
Highstreet Mobile's mission is to connect people to the brands they love. We are a team of makers and we've built a SaaS product for fashion brands. We enable brands to give an amazing shopping experience to their customers. Our customers get a native mobile shopping app for Android and iOS that we constantly refine and extend.
You'll be joining the team that is responsible for the core library that powers our Android apps. The core library provides all app capabilities, from API calls to UI, but can be extended to meet customer needs. We care deeply about the user experience and you'll be working closely with the design team when implementing new features and improvements. Our automated unit tests and extensive code reviews make sure code quality remains up to par.
Highstreet Mobile | Android Engineer | Utrecht (near Amsterdam), The Netherlands | Onsite/Remote (EU) | Full Time | https://www.highstreetmobile.com
Highstreet Mobile's mission is to connect people to the brands they love. We are a team of makers and we've built a SaaS product for fashion brands. We enable brands to give an amazing shopping experience to their customers. Our customers get a native mobile shopping app for Android and iOS that we constantly refine and extend.
You'll be joining the team that is responsible for the core library that powers our Android apps. The core library provides all app capabilities, from API calls to UI, but can be extended to meet customer needs. We care deeply about the user experience and you'll be working closely with the design team when implementing new features and improvements. Our automated unit tests and extensive code reviews make sure code quality remains up to par.
Highstreet Mobile | Android Engineer | Utrecht (near Amsterdam), The Netherlands | Onsite/Remote (EU) | Full Time | https://jobs.highstreetmobile.com/android-engineer/en
Highstreet Mobile's mission is to connect people to the brands they love. We are a team of makers and we've built a SaaS product for fashion brands. We enable brands to give an amazing shopping experience to their customers. Our customers get a native mobile shopping app for Android and iOS that we constantly refine and extend.
You'll be joining the team that is responsible for the core library that powers our Android apps. The core library provides all app capabilities, from API calls to UI, but can be extended to meet customer needs. We care deeply about the user experience and you'll be working closely with the design team when implementing new features and improvements. Our automated unit tests and extensive code reviews make sure code quality remains up to par.
Highstreet | iOS Engineer | Utrecht, The Netherlands | Onsite
We're building a native app platform that powers retail apps for brands around the world. We're a small team of engineers in a growing company (~15 people in total), focussed on building innovative apps with an excellent user experience and that deliver business to our customers.
We're looking for iOS Engineers with experience in creating well-architected mobile apps that offer a great user experience. When you come work with us, your first code is guaranteed to ship within two weeks. We care about our process to ensure bugs are caught, in your code and mine. We have a shared sense of responsibility throughout the company to keep complexity to a minimum and care about code quality. We're not just building for the now, we're in it for the long run.
At Highstreet, we build a platform for native mobile shopping apps that end-users love and delivers business to our customers, which are mostly fashion brands from all around the globe.
We are looking for a full-time back-end developer, who is excited to innovate mobile shopping. Would you like to build a robust, scalable platform that serves data to our apps around the globe. You will be joining our small but smart team with a start-up attitude. There is plenty of room for your ideas and initiatives on how to improve our platform.
I lead the iOS and Android teams at Highstreet and would love to talk to you if you're interested! Our interview process consists of a phone screening, in person/Skype interview, take-home assignment and a discussion in person/over Skype of the assignment.
I think Blendle is doing a great job regarding reducing friction. I signed up and read my first article through the service yesterday within one minute after somebody in my Twitter feed shared it. The per-article fee is subtracted from my account as I read, but I can ask money back if I didn't like the article.
In my own experience, it is not only about starting simple, but also finishing it simple. I know you're not saying it isn't, but what I want to emphasize is that it is too easy to say that you're done with something simple and then move on to the next/bigger thing. For example, what eru suggested, if you build a Tetris-like game. You probably can have the gameplay finished in a few hours. And then, move on? Or spend another week on polishing, menu's, sound, graphics, copy, etc. I think the most valuable part of the lesson of starting simple is in finishing it. (And they don't tell you that.)
This is probably the best hidden advice on this page. Build complete projects. Make it a habit. If you just make gameplay prototypes, that will become your habit and you'll struggle to ship your big idea when the time comes. You'll be missing the final 90%. You won't know how to prep game art for example.
This applies to all creative "package" projects. Learn to ship.
Many of the chemo medications she got have been a stable of AML treatment for decades. From what I understood from our doctors, the improvement in survival rate for AML has come from supportive care, i.e. the ability to keep the patient alive during treatment. Treatment of bacterial and fungal infections has gotten a lot better.
AML is a very heterogeneous disease. The treatment depends a lot on the specific mutations the patient has. Research can only focus on so many target mutations at a time. We did see the progress over the three years we were there. I have high hopes that children with the same mutation as my daughter will in the near future have better chances, specifically thanks to menin inhibitors.